First G-CSF stimulation injection was given subcutaneously at 11pm. I will get another at 3am.
G-CSF stands for Biosimilar granulocyte colony-stimulating factors. (10 ug/kg (5 days) in combination with Methylprednisolone 500mg/d I.v. (5 days)).
How G-CSF works:
Growth factors are proteins made in the body. Some of them make the bone marrow produce blood cells. G-CSF is a type of growth factor that makes the stem cells move from the bone marrow into the blood. Stem cells are the cells in the bone marrow that make red blood cells, white cells and platelets.
Before a stem cell transplant, you have G-CSF to stimulate the bone marrow to produce stem cells and release them into the blood. The stem cells are collected and then you have high dose chemotherapy.
The high dose chemotherapy stops your bone marrow producing blood cells. On transfusion the stem cells are put back into your bloodstream from where they go into the bone marrow and start making the different types of blood cells again. After chemotherapy the white blood cells which fight infection are called neutrophils. When your body is low in white blood cells you are neutropenic and need to be kept in isolation and free from infection.